AbboMax Announces The Availability Of New Methyl-specific Antibodies

Online, October 20, 2010 (Newswire.com) - AbboMax offers nine novel anti- histone H3 antibodies specific for a mono-, di-, or tri-methylated state of Lys4, Lys9, and Lys27.

Methylation is involved in regulation of gene expression, protein function and RNA metabolism. The methylation of specific residues in the histone tails is a central modification for regulating epigenetic transitions in chromatin. Methylation of histone H3 on lysines 9, 27, and histone H4 on lysine 20 is associated with heterochromatin and some repressed genes with euchromatin. Histones are basic nuclear proteins that together with DNA make up the nucleosome structure in eukaryotes.

AbboMax is a biotechnology company headquartered in San Jose, California, USA. The company offers innovative primary and secondary antibodies, antibody reagents, assay kits, and liposome reagents, as well as custom services.