OZ Biosiences : Capture and Concentrate Virus

Online, November 19, 2012 (Newswire.com) - OZ Biosciences SAS, specialized in the development of innovative transfection technologies is delighted to announce the launching of new products Mag4C Kits.

Mag4C Kits are specifically developed for capturing, concentrating and storing viruses. These kits are composed of 3 reagents allowing Magnetic Capture/Concentration, Elution and Conservation of viruses.

"We continuously improve our core technology", explains Olivier Zelphati, CEO of OZ Biosciences. Indeed, Mag4C Kits are new specific superparamagnetic nanoparticles formulation evolved from our Magnetofection™ Technology.

Mag4C magnetic nanoparticles capture by electrostatic and hydrophobic interactions viruses in culture medium with 80-99 % efficiency. Simple, rapid and ready to use this product allows concentrating virus by magnetic capture in 30-45 minutes. In this way, ultracentrifugation, precipitation and chemicals are avoided. Once captured onto magnetic beads, viruses can be:

(1) Concentrated and stored with the Conservation Buffer or directly used for cell culture, molecular biology or other assays.

(2) Concentrated, eluted from the magnetic beads with the Elution Buffer and stored with the Conservation Buffer or used for various assays.

Moreover, these kits contain particular conservation buffers that improve virus stability upon storage conditions.

For in vitro and in vivo infection. Mag4C beads are compatible with the Magnetofection™ technology. This method allows concentrating the entire viral dose on the cells very rapidly, accelerating the transduction process and infecting non-permissive cells. Moreover, virus infection efficiency is significantly increased and cell adsorption/infection can be synchronized without modification of the viruses.

Two differents kits are available depending on the virus:
Mag4C-Ad kit for adenoviruses & Mag4C-Lv kit for lentiviruses and retroviruses.

You can find more information at www.ozbiosciences.com